Senior Scientist - Bioanalytical & Biomarker Technologies

We are seeking a highly motivated bioanalytical scientist who can contribute to the development and implementation of state-of-the-art quantitative and qualitative analytical and bioanalytical methods to support biopharmaceuticals in discovery and preclinical development pipeline at Regeneron. The successful candidate need function well in a collaborative, fast-paced, multidisciplinary team environment.

A Typical day in this role looks like:

• Primarily responsible for developing LC‑MS–based bioanalytical methods in various biological matrices.
• Apply these methods to quantify biotherapeutic levels, assess in vitro stability, evaluate in vivo biotransformation, and measure biomarkers (small molecules, peptides, and proteins).
• Support characterization of drug candidates and critical reagents within the discovery pipeline.
• Collaborate closely with chemistry, conjugation, biology, PK, and TK teams to ensure strong experimental design, accurate data interpretation, and informed decision‑making.
• Contribute to advancing programs involving bioconjugates, oligonucleotides, bispecifics, and other therapeutic modalities.
• Explore and evaluate innovative bioanalytical technologies and emerging platforms to support an evolving portfolio, including novel molecular modalities and therapeutic areas.
• Document experiments, results, and findings in an electronic lab notebook.
• Present scientific work at internal and external meetings.
• Perform general lab and instrument maintenance.
• Grow into the role of bioanalytical representative on cross‑functional project teams, effectively managing priorities to meet multiple project goals and timelines.

This role may be for you if you have experience:

• Chemistry, Biochemistry, Pharmaceutical Science or a related discipline, B.S. with 10+ yrs, MS with 8+ yrs, or Ph.D. with 0-6 yrs postdoctoral experience.
• Proven expertise and extensive experience in liquid chromatography and mass spectrometry is required, with demonstrated track record of successfully developing MS, LC-MS or LC-MS/MS method.
• Hands on experience in sample preparation technique (LLE, SPE, Immunocapture, enzymatic digestion, homogenization etc.) and automation platform.
• Scientific curiosity and strong capabilities in experimental design, execution, data interpretation and troubleshooting with limited supervision.
• Ability to think critically and to prioritize and manage multiple projects under aggressive timeline in a fast-paced environment.
• Detail-oriented, good interpersonal and effective technical writing and verbal communication skills.
• Industrial experience in bioanalysis of LC-MS based small molecule, siRNA, biomarkers and biotherapeutics assay development is preferred. Job level may be adjusted based on the experience.
• Previous experience in GLP lab and mass spectrometry applications in ADC analytics, metabolomics and proteomics would be advantageous.

Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

Where necessary, we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits. Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other locations, additional information will be provided during the recruitment process. If you have any questions, please speak with your recruiter.

Please be advised that at Regeneron, we believe we do our best work when we are together. For that reason, many roles are required to be performed on‑site. Please speak with your recruiter and hiring manager for more information about on‑site expectations for your role and location.

As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications.

For jobs in Canada: this posting is for an existing position.

Salary Range (annually)