Description d’emploi
We are seeking a dynamic senior associate scientist to join bioanalytical & biomarker technologies group. The candidate will design and execute analytical and bioanalytical method to support biotherapeutics discovery and preclinical development. The individual should be experienced in executing HPLC and/or LC-MS based methods from sample preparation, instrument operation to data analysis. The successful candidate will be expected to work cross-functionally in a collaborative, fast-paced, multidisciplinary team environment and have the opportunity to explore new technologies while growing technical depth.
A Typical day in this role looks like:
- Design, execute, and troubleshoot LC‑MS and HPLC methods for analytical characterization of bioconjugates and bioanalytical quantification of therapeutics.
- Support a range of modalities—including monoclonal antibodies (mAbs), antibody–drug conjugates (ADCs), siRNA/oligonucleotides, and endogenous biomarkers—across diverse biological matrices.
- Perform end‑to‑end sample preparation (e.g., LLE, SPE, affinity capture, enzymatic digestion, homogenization) and operate LC‑MS/MS workflows from instrument setup to data analysis.
- Analyze and interpret results; summarize findings, propose next steps, and present data at internal meetings.
- Document experiments, methods, and results in electronic lab notebooks (ELNs) with clarity and rigor; contribute to SOPs and method documentation.
- Maintain instruments and general lab readiness; troubleshoot systems and ensure data integrity and instrument uptime.
- Evaluate and implement new platforms, workflows, and automation to improve throughput, sensitivity, and robustness.
- Prioritize effectively across multiple projects and timelines, collaborating closely with colleagues in discovery biology, DMPK/PK‑PD, and process/analytical teams.
This role may be for you, if you have experience:
- BS or MS degree in Chemistry, Biochemistry, Pharmaceutical Science or a related discipline with 3+ years hand-on experience.
- Experience in liquid chromatography and/or mass spectrometry is preferred, with the ability to execute, qualify and optimize analytical methods.
- Hands on experience in sample preparation techniques (LLE, SPE, affinity capture, enzymatic digestion, homogenization, etc.); experience with automation platforms is a plus.
- Detail-oriented, good interpersonal and effective technical communication skills (written and verbal).
- Ability to manage multiple projects in a fast-paced environment.
- Collaborative team player with a growth mindset to quickly adapt to evolving priorities and continuously learn to embrace new challenges.
- Previous exposure in bioanalysis of LC-MS based small molecule, oligonucleotides, biomarkers and biotherapeutics assay development is beneficial.
Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.
Where necessary, we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits. Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other locations, additional information will be provided during the recruitment process. If you have any questions, please speak with your recruiter.
Please be advised that at Regeneron, we believe we do our best work when we are together. For that reason, many roles are required to be performed on‑site. Please speak with your recruiter and hiring manager for more information about on‑site expectations for your role and location.
As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications.
For jobs in Canada: this posting is for an existing position.
Salary Range (annually)
$80,300.00 - $131,100.00