Senior Associate Scientist, Obesity Muscle & Metabolism

The Obesity, Muscle and Metabolism group is seeking an enthusiastic Associate Scientist to advance our exciting discovery and translational programs focused on metabolic disease, skeletal muscle biology, and energy balance. The successful candidate will drive hands-on experimental work in cellular and in vivo systems, develop robust assays, and collaborate across biology, chemistry, pharmacology, and data science to generate decision-making data for pipeline programs. This is a lab-focused role suited for an experienced bench scientist with a strong foundation in metabolic biology. Depending on level, you will independently execute studies, contribute to study design, and influence project strategy. You will work across adipose and muscle biology, insulin signaling, mitochondrial function, and physiological readouts pertinent to obesity and related metabolic disorders.

As a Sr Associate Scientist, a typical day may include:

• Support or lead in vivo studies in rodent models of obesity, insulin resistance, and muscle dysfunction including compound dosing, tissue collection, and metabolic phenotyping

• Conduct follow-up analysis of metabolic tissues from in vivo studies using qPCR, western blotting, immunohistochemistry and RNAScope

• Design, execute, and troubleshoot in vitro experiments in primary and immortalized cell models of adipocytes and myotubes including differentiation, stimulation, and compound testing.

• Analyze and interpret data using appropriate statistical methods and clearly communicate findings in written reports and presentations

• Maintain meticulous electronic lab notebooks, SOPs, and assay documentation to ensure data integrity and reproducibility

This role may be for you if:

• You enjoy working in a fast-paced environment

• You are a fast learner and have desire to expand your skill set and learn new techniques

• You are detail oriented, well-organized and can multi-task

• You are a team player

• You have strong communication skills

To be considered, you must have: In Vivo experience. BS or MS in Cell Biology, Physiology, Molecular Biology, Pharmacology, or related discipline. Minimum of 3+ years of laboratory experience, preferably working with mouse models. Experience designing and executing metabolic studies in rodent models of obesity including indirect calorimetry, glucose and insulin tolerance testing, assessing food intake and body composition Competence with data analysis and visualization tools such as Excel, Prism, R, or Python and sound understanding of experimental design and statistics. Excellent presentation, time management, and collaborative skills. Preferred Additional Qualifications- Tissue culture, western blotting, ELISA and flow cytometry experience in various cell lines.Histologic experience with metabolic tissues including liver, skeletal muscle, pancreas and brain.

Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

Where necessary, we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits. Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other locations, additional information will be provided during the recruitment process. If you have any questions, please speak with your recruiter.

Please be advised that at Regeneron, we believe we do our best work when we are together. For that reason, many roles are required to be performed on‑site. Please speak with your recruiter and hiring manager for more information about on‑site expectations for your role and location.

As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications.

For jobs in Canada: this posting is for an existing position.

Salary Range (annually)