Descripción de funciones
The Obesity, Muscle and Metabolism group is seeking an enthusiastic Associate Scientist to advance our exciting discovery and translational programs focused on metabolic disease, skeletal muscle biology, and energy balance. The successful candidate will drive hands-on experimental work in cellular and in vivo systems, develop robust assays, and collaborate across biology, chemistry, pharmacology, and data science to generate decision-making data for pipeline programs. This is a lab-focused role suited for an experienced bench scientist with a strong foundation in metabolic biology. Depending on level, you will independently execute studies, contribute to study design, and influence project strategy. You will work across adipose and muscle biology, insulin signaling, mitochondrial function, and physiological readouts pertinent to obesity and related metabolic disorders.
As a Sr Associate Scientist, a typical day may include:
Support or lead in vivo studies in rodent models of obesity, insulin resistance, and muscle dysfunction including compound dosing, tissue collection, and metabolic phenotyping
Conduct follow-up analysis of metabolic tissues from in vivo studies using qPCR, western blotting, immunohistochemistry and RNAScope
Design, execute, and troubleshoot in vitro experiments in primary and immortalized cell models of adipocytes and myotubes including differentiation, stimulation, and compound testing.
Analyze and interpret data using appropriate statistical methods and clearly communicate findings in written reports and presentations
Maintain meticulous electronic lab notebooks, SOPs, and assay documentation to ensure data integrity and reproducibility
This role may be for you if:
You enjoy working in a fast-paced environment
You are a fast learner and have desire to expand your skill set and learn new techniques
You are detail oriented, well-organized and can multi-task
You are a team player
You have strong communication skills
To be considered, you must have: In Vivo experience. BS or MS in Cell Biology, Physiology, Molecular Biology, Pharmacology, or related discipline. Minimum of 3+ years of laboratory experience, preferably working with mouse models. Experience designing and executing metabolic studies in rodent models of obesity including indirect calorimetry, glucose and insulin tolerance testing, assessing food intake and body composition Competence with data analysis and visualization tools such as Excel, Prism, R, or Python and sound understanding of experimental design and statistics. Excellent presentation, time management, and collaborative skills. Preferred Additional Qualifications- Tissue culture, western blotting, ELISA and flow cytometry experience in various cell lines.Histologic experience with metabolic tissues including liver, skeletal muscle, pancreas and brain.
Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We have an inclusive culture that provides comprehensive benefits, which vary by location. In the U.S., benefits may include health and wellness programs (including medical, dental, vision, life, and disability insurance), fitness centers, 401(k) company match, family support benefits, equity awards, annual bonuses, paid time off, and paid leaves (e.g., military and parental leave) for eligible employees at all levels! For additional information about Regeneron benefits in the US, please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other countries’ specific benefits, please speak to your recruiter.
Please be advised that at Regeneron, we believe we are most successful and work best when we are together. For that reason, many of Regeneron’s roles are required to be performed on-site. Please speak with your recruiter and hiring manager for more information about Regeneron’s on-site policy and expectations for your role and your location.
Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. The Company will also provide reasonable accommodation to the known disabilities or chronic illnesses of an otherwise qualified applicant for employment, unless the accommodation would impose undue hardship on the operation of the Company's business.
For roles in which the hired candidate will be working in the U.S., the salary ranges provided are shown in accordance with U.S. law and apply to U.S.-based positions. For roles which will be based in Japan and/or Canada, the salary ranges are shown in accordance with the applicable local law and currency. If you are outside the U.S, Japan or Canada, please speak with your recruiter about salaries and benefits in your location.
Please note that certain background checks will form part of the recruitment process. Background checks will be conducted in accordance with the law of the country where the position is based, including the type of background checks conducted. The purpose of carrying out such checks is for Regeneron to verify certain information regarding a candidate prior to the commencement of employment such as identity, right to work, educational qualifications etc.
Salary Range (annually)