Process Development Engineer II, Analytical Sciences: Synthetic and Bioconjugation Scale-Up Technologies (SBST)

Regeneron’s Preclinical Manufacturing & Process Development (PMPD) organization in Tarrytown, NY is seeking a highly motivated Process Development Engineer II to join our Synthetic and Bioconjugation Scale-up Technologies (SBST) Analytics group. In this role, you will serve as the analytical lead to develop fit-for-purpose analytical methods to characterize critical intermediates (small molecules, siRNA, and/or peptides) to support our growing and diverse bioconjugate pipeline. You will lead and implement analytical deliverables working closely with cross-functional teams and external collaborators (CDMOs) to advance bioconjugate programs from development to commercialization.

A Typical Day in the Role of Process Development Engineer II Might Look Like:

• Design and execute analytical testing, method development and characterization of critical intermediates to enable bioconjugate development.

• Compile, analyze, and interpret complex datasets; connect key findings across experiments and propose clear, actionable next steps.

• Communicate results and recommendations clearly to technical and non-technical audiences to enable timely, data-driven decisions.

• Serve as the analytical lead for critical intermediates and bioconjugates; coordinate internal and external analytical deliverables (development, transfer, and troubleshooting) to support program milestones.

• Provide technical support and troubleshooting to receiving labs to keep analytical activities off the critical path.

• Author high-quality documentation (e.g., procedures, method development reports, characterization reports, ELN entries) to support program timelines.

• Build and improve business workflows for documentation standardization, data digitization, and sample management.

• Maintain compliance with lab and environmental safety and promote a safe lab culture.

• Support equipment upkeep, troubleshooting, maintain an organized workspace, and proactively plan for lab resources.

• Train and mentor peers and junior team members as needed (directly and/or indirectly).

This Role May Be For You If You:

• Enjoy hands-on lab work and consistently generate high-quality, reproducible data.

• Take initiative, deliver on challenging work, and learn new technologies quickly.

• Have hands-on experience with analytical techniques for synthetic molecules (i.e., peptide, siRNA, and small-molecule) characterization and relevant software’s.

• Possess a customer-centric mindset to analytical development and understand how analytical deliverables enable program decisions across drug development in different phases of the program

• Thrive in a fast-paced, highly collaborative environment working on complex problems.

• Communicate clearly (written and verbal), simplify messages for impact, and build strong working relationships.

• Think critically and apply strong problem-solving skills, and comfortable navigating ambiguity.

This role requires B.S. with 6+ years of relevant experience, or M.S. with 4+ years of relevant experience, in analytical chemistry, biochemistry, biology, chemical engineering, or a related field. Hands-on experience with analytical method development for synthetic molecules (e.g., small molecules, PEG, peptides, and/or oligos), i.e. electrophoresis, HPLC, MS, UV spectroscopy and associated software (e.g., Empower). Experience transferring methods to internal/external development labs, and troubleshooting. Demonstrated experience serving as an analytical lead, working with internal teams and external CDMOs. Strong written and verbal communication skills, including the ability to present data clearly to diverse audiences. Ability to work with minimal guidance and collaboratively across cross-functional teams, with strong attention to detail and documentation practices. Demonstrated initiative, learning agility, and a growth mindset in a fast-paced environment. Experience with antibodies and/or bioconjugates is strongly preferred.

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Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

Where necessary, we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits. Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other locations, additional information will be provided during the recruitment process. If you have any questions, please speak with your recruiter.

Please be advised that at Regeneron, we believe we do our best work when we are together. For that reason, many roles are required to be performed on‑site. Please speak with your recruiter and hiring manager for more information about on‑site expectations for your role and location.

As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications.

For jobs in Canada: this posting is for an existing position.

Salary Range (annually)