Scientist - Bispecifics and Antibody Engineering

Build our future together:

At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking a results-driven Scientist to join our Bispecifics and Antibody Engineering Department, supporting the production, purification, and functional characterization of next-generation antibodies across multiple programs. In this role, your work will directly impact the therapeutic pipeline while contributing to the development of new platform capabilities, in a fast-paced environment alongside diverse, cross-functional teams.

This position offers the opportunity to contribute to a fast-growing, science-driven organization making a meaningful difference to patients worldwide.

When & where:

• Location: Tarrytown, NY

• Work model/flexibility: Onsite

Discover your role:

• Perform molecular biology techniques to generate expression constructs, including DNA isolation and sequence confirmation

• Conduct transfections for protein production at multiple scales

• Purify biologics using chromatography platforms, including affinity, ion exchange (IEX), and size-exclusion chromatography on ÄKTA systems

• Characterize proteins via immunoblotting, SDS-PAGE, thermal stability, and UV/Vis spectrophotometry

• Perform properly controlled biochemical and cell-based assays (e.g., ELISA, AlphaLISA, flow cytometry, phagocytosis, cell activation, and cytolytic assays)

• Troubleshoot bioanalytical and cell-based assay data to inform iterative optimization

• Collaborate with colleagues to evaluate biological function in vivo

• Maintain accurate records in Benchling and electronic lab notebooks (ELN)

This role requires:

• B.Sc., M.Sc., or related degree in molecular biology, cell biology, biochemistry, immunology, or a related field, with 5+ years of relevant academic or industry experience

• Strong attention to detail and a rigorous approach to experimentation

• Excellent organizational, communication, and presentation skills

• Ability to prioritize and adapt quickly to evolving program directions and timelines

• Preferred: hands-on experience with cloning, antibody expression, antibody purification and characterization, and cell-based bioassays

• Preferred: experience with in vivo disease modeling

Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

Where necessary, we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits. Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other locations, additional information will be provided during the recruitment process. If you have any questions, please speak with your recruiter.

Please be advised that at Regeneron, we believe we do our best work when we are together. For that reason, many roles are required to be performed on‑site. Please speak with your recruiter and hiring manager for more information about on‑site expectations for your role and location.

As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications.

For jobs in Canada: this posting is for an existing position.

Salary Range (annually)