At RGC, we are driven by a passion to advance science and enhance people’s lives through the power of genetics. Human ingenuity, constant collaboration, innovative technology and advanced analytics have allowed us to create one of the world’s largest and most diverse genomic databases.
Our team of world-class researchers and scientists are using this constantly expanding database to identify novel drug targets, clinical indications and important genomic biomarkers for pharmacogenomic applications. As a uniquely integrated research initiative, our work has meaningful impact in speeding drug discovery and development, as we seek to turn the promise of genetics into important new medicines for patients around the globe.
“REGENIE is viewed by many as the new standard tool in statistical genetics to help advance the research capabilities of the scientific community. The REGENIE methodology has been used to more efficiently analyze case control studies, manage a large number of phenotype samples, as well as handle imbalances in the data.”
– Joelle Mbatchou, PhD, Manager, Statistical Geneticist at RGC
“What’s different about this expedition, is that we had to leave behind the traditional way of looking at genetic data. When we found a gene like GPR75, that has rare variants that are strongly protective against obesity, it vindicates the expedition.”
– Manuel Ferreira, PhD, Executive Director, Statistical Genetics at RGC
COLLABORATING FOR BETTER SCIENCE Collaborations with leading institutions and researchers are the backbone of our success. We work with a diverse global network of more than 110 institutions in 23 countries. One of our largest and foundational collaborations is with UK Biobank, pioneers in collecting long-term genetic and real-world health information from half a million participants.
HARNESSING THE POWER OF DIVERSITY To create medicines for all, we need to understand how genetics may impact health differently in different people. To combat the historic homogeneity of genetic research, we have created one of the most diverse genomic databases in the world. We have sequenced more than 500,000 individuals from underrepresented population and continue our efforts to ensure our research reflects the breadth of the world around us.