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Postdoctoral Fellow, Human Aging Genetics

Job Description

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The Founder and Special Populations (FPS) group at the Regeneron Genetics Center (RGC) seeks a versatile and innovative postdoc in human aging genetic and associated diseases.

This project will focus on a) identifying genetic factors contributing to resilience to age-related diseases and traits, b) identifying novel genetic variants associated with healthy aging, and c) understanding the complex interaction between genetic variants and environmental factors in longevity. You will implement the project by learning and applying a range of statistical genetics methods such as genome/exome-wide association analysis, fine mapping of genetic variants, phenome-wide association analysis, survival analysis, polygenic and clinical risk scores, and Mendelian randomization to incomparable RGC human genetic datasets.

In this role, a typical day might include:

  • In-depth literature review to understand the research question and keep up to date with current research in the field of aging genomics.

  • Conducting innovative and creative research to address a novel scientific question under the auspices of scientist mentors.

  • Generating clinical and phenotype datasets with the clinical informatics team for genetic analysis.

  • Performing genome/exome-wide association analysis using sophisticated bioinformatics and statistical genetics tools such as REGENIE.

  • Deep diving to understand the genes' functions and their relevance to aging biology.

  • Generating and analyzing polygenic and clinical risk scores.

  • Presenting data internally, including at TAG meetings, trainee meetings, and companywide seminars.

  • Providing ongoing reports of research progress to supervisors and program staff.

  • Presenting data at major external conferences and publish in high-profile peer-reviewed journals.

  • Assisting with mentoring and instructing high-school, undergraduate, and graduate school interns.

  • Participating in postdoctoral program activities such as weekly meetings, seminars, and the annual postdoc retreat.

This role may be for you if:

  • You are a curious, creative thinker and a standout colleague with a track record of research productivity (publications).

  • You strongly desire to contribute to cutting-edge genetics research on understanding the genomics of healthy aging and age-related diseases.

  • You have outstanding data analytical skills with expertise in genetic association analysis, fine mapping, rare variants and gene burden analysis, survival analysis, risk score assessment, and Mendelian randomization.

  • You have strong communication and presentation skills.

  • You enjoy participating and collaborating in cross-functional projects that involve multiple teams.

To be considered for this role, you must have a Ph.D. or MD/Ph.D. in human genetics, computational biology, bioinformatics, or statistical genetics. We seek someone with hands-on experience in analytical genetics, genome/exome-wide association studies, survival analysis, Mendelian randomization, rare variants, gene burden analysis, phenome-wide association analysis, and fine mapping. Expertise in cloud-based genetic data analysis using R or Python computer programming language is highly desired. You will have the opportunity to lead a fast-paced aging genomics research project in a results-driven environment, with feedback from leaders in the aging and human genomics field. #postdoc #postdoctoral #earlycareers

Does this sound like you? Apply now to take your first steps toward living the Regeneron Way! We have an inclusive and diverse culture that provides comprehensive benefits including health and wellness programs, fitness centers and equity awards, annual bonuses, and paid time off for eligible employees at all levels!

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. We will ensure that individuals with disabilities are provided reasonable accommodations to participate in the job application process. Please contact us to discuss any accommodations you think you may need.

The salary ranges provided are shown in accordance with U.S. law and apply to U.S. based positions, where the hired candidate will be located in the U.S. If you are outside the U.S, please speak with your recruiter about salaries and benefits in your location.

Salary Range (annually)

$69,500.00 - $113,500.00