The Viral Delivery Technologies (VDT) group within the Regeneron Genetics Medicines department is seeking a curious and motivated Associate Scientist to join our fast-paced team and support our efforts to characterize novel viral vectors in vivo. This is an exciting opportunity for a researcher with a background in animal handling and manipulation of mouse models to grow their career in the Gene Therapy space by helping advance innovative AAV and lentivirus-based therapeutic platforms.
As an In Vivo Associate Scientist in the VDT group, a typical day may include the following:
- Inject mice via different routes (IP, IV, RO, Subcutaneous, intramuscular); collect blood and tissue samples in the vivarium.
- Monitor biodistribution of viral vectors through in vivo bioluminescent imaging (IVIS)
- Dissociate tissues and prepare samples for subsequent cellular enrichment or characterization.
- Work at the bench running ELISAs, qPCR, Western Blots, Flow Cytometry and/or perform immunohistochemistry and in situ hybridization (RNAscope) on automated equipment (Ventana type).
- Acquire images of IHC and RNAscope samples by microscopy.
- Conduct data analysis using programs such as Excel, Prism, and HALO.
- Update notes and make PowerPoint slides to summarize projects and data.
- Present data both formally and informally and help plan/coordinate follow-up work.
- Maintain lab supplies and help with lab organization
This role may be for you if:
- You are comfortable with quickly shifting priorities and enjoy working in a fast-paced, collaborative environment to develop new technologies.
- You are skilled in designing well-controlled experiments that can provide reliable results.
- You have excellent organization and communication skills, are detail-oriented, and take stellar notes.
- You possess the ability to analyze data, extract conclusions and present them at various meetings.
- You are interested in expanding your technical skill set, can learn on the job, and are capable of rapidly applying newly learned skills.
To be considered for this role, you must have a MS or a BS and up to 2+ years of relevant experience. Experience with animal handling, animal injections (particularly tail vein or retro-orbital), bleeds (retro-orbital, submandibular, tail vein) dissection techniques and basic histology / immunohistochemistry techniques is required. Experience with bioluminescent imaging, virology, ELISAs, western-blotting, flow cytometry, immune cell isolation and microscopy will be a distinct advantage, but can be trained. You must be willing to work in a BSL 2/3 lab!!
Does this sound like you? Apply now to take your first steps toward living the Regeneron Way! We have an inclusive and diverse culture that provides comprehensive benefits including health and wellness programs, fitness centers and equity awards, annual bonuses, and paid time off for eligible employees at all levels!
Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. We will ensure that individuals with disabilities are provided reasonable accommodations to participate in the job application process. Please contact us to discuss any accommodations you think you may need.
The salary ranges provided are shown in accordance with U.S. law and apply to U.S. based positions, where the hired candidate will be located in the U.S. If you are outside the U.S, please speak with your recruiter about salaries and benefits in your location.
Salary Range (annually)