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Senior Associate Scientist- Biomolecular Interaction Analysis

Job Description

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We are seeking a Senior Associate Scientist to join our Antibody Therapeutic group. In this role, you will carry out label-free quantitative analysis of macromolecular interaction for therapeutic monoclonal antibodies development programs.

As a Senior Associate Scientist, a typical day may include:

  • Independently design, execute, and troubleshoot SPR and BLI-based assays, including binding kinetics, blocking, affinity, competition, and epitope binning

  • Supporting Antibody Discovery interaction using Biacore and complementary label-free real-time technologies for protein reagents validation, upstream antibody screening, and late stage therapeutic antibody leads characterization

  • Perform routine biosensor (SPR/BLI) based biomolecular interaction experiments, data analysis

  • Maintain the operation of label free instruments.

This Role Might Be for You If:

  • You have the ability to critically analyze and troubleshoot scientific problems.

  • You have strong scientific initiative and ability to multi-task, prioritize work and handle multiple projects.

  • You have the ability to work independently but also within a collaborative team environment and have flexibility to work on changing priorities.

  • You have excellent written and verbal communication skills

In order to be considered for this role, you must have at least a BS/MS with 3-5+ years of relevant experience in related field. We need someone with experience using protein purification (HPLC, FLPC, ion-exchange, affinity, size exclusion chromatography, and protein conjugation chemistry) and protein analysis techniques (SDS-PAGE, Western-blot, ELISA). A solid understanding of structural biology, biophysics, and chemical biology is advantageous. Knowledge and experience in using biophysical methodologies, such as Biacore, Octet, or ITC, to study protein/small molecule- protein interaction and binding kinetics preferred. Experience with in-vitro molecular interaction/characterization using biosensor such as Biacore/Octet a plus.

Does this sound like you? Apply now to take your first steps toward living the Regeneron Way! We have an inclusive and diverse culture that provides comprehensive benefits including health and wellness programs, fitness centers and equity awards, annual bonuses, and paid time off for eligible employees at all levels!
Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. We will ensure that individuals with disabilities are provided reasonable accommodations to participate in the job application process. Please contact us to discuss any accommodations you think you may need.
The salary ranges provided are shown in accordance with U.S. law and apply to U.S. based positions, where the hired candidate will be located in the U.S. If you are outside the U.S, please speak with your recruiter about salaries and benefits in your location.

Salary Range (annually)

$75,700.00 - $123,500.00