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Sr Scientist, Peptide MHC Bioassay Development

Job Description

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Regeneron's Therapeutic Proteins Bioassay Group, located in Tarrytown, NY, seeks a highly motivated and passionate Sr. Scientist to join our team.

In this role, you will focus on developing cell-based assays and high throughput screening methods to support the identification of therapeutic antibodies, chimeric antigen receptors (CARs), and T cell receptors (TCRs) that target major histocompatibility complex (MHC) presented tumor antigens.

A Typical Day In the Role of Sr Scientist Might Look Like:

  • Develop, optimize, and execute high throughput cell-based assays (viability/cytotoxicity, luciferase reporter, cytokine release, flow cytometry, imaging)
  • Isolate, phenotype, and expand human T cells
  • Develop in vitro T cell functional assays
  • Cell line engineering (over-expression via Lentiviral transduction/CRISPR mediated KO/KI)
  • Lead, guide, and work with other Scientists to support multi-functional teams
  • Communicate/coordinate activities, prepare and present data in cross-functional meetings
  • Stay ahead of technological/scientific developments

This Role Might Be For You If You Have:

  • A Passion for cell-based assay development and drug discovery
  • Strong background in immunology
  • Teamwork and problem solving in a fast-paced environment
  • Excellent verbal/written communication and organizational skills

This role requires a PhD in Immunology or related field and 0-3+ years, an MS with 5+ or a BS with 8+ years of relevant experience. Experience engineering cell lines is needed. Experience culturing T cells a plus. Flow cytometry expertise a plus. The ideal candidate should have experience developing, optimizing, and troubleshooting immune cell functional assays and a background in MHC/TCR biology.

Does this sound like you? Apply now to take your first steps toward living the Regeneron Way! We have an inclusive and diverse culture that provides comprehensive benefits including health and wellness programs, fitness centers and equity awards, annual bonuses, and paid time off for eligible employees at all levels!
Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. We will ensure that individuals with disabilities are provided reasonable accommodations to participate in the job application process. Please contact us to discuss any accommodations you think you may need.
The salary ranges provided are shown in accordance with U.S. law and apply to U.S. based positions, where the hired candidate will be located in the U.S. If you are outside the U.S, please speak with your recruiter about salaries and benefits in your location.

Salary Range (annually)

$103,600.00 - $169,000.00